Resteeme Injectable Bioregenerators

Regenerative Aesthetics, Re-Engineered

Retix.C is developed by the French pharmaceutical company, URGO Group, a global leader in skin physiology with over 60 years of expertise in wound healing, skin protection, regeneration, and texture optimisation.

The brand is founded on the principle of stimulating the skin’s natural regenerative and revitalisation processes. Retix.C offers clinically driven, professional treatments tailored to individual skin needs, supported by targeted home care solutions. All formulations are developed and manufactured in accordance with the highest pharmaceutical standards, under strict quality control aligned with ISO 13485 certification, and their efficacy is validated through clinical and instrumental studies.

What Makes Resteem Different?

Resteem™ is engineered to target core mechanisms of skin ageing, specifically:

Glycation (AGEs formation)
Oxidative stress
Chronic inflammation pathways (NF-κB activation)

These processes directly damage collagen, elastin, and the extracellular matrix, accelerating visible ageing. By addressing these mechanisms, Resteem™ delivers functional skin regeneration, not just surface-level improvement.

X-Treme Technology: Multi-Level Regeneration

At the core of Resteem™ is a broad spectrum of hyaluronic acid chain lengths, combined with trehalose, forming a three-dimensional molecular structure within the dermis.

This enables:

Enhanced fibroblast stimulation and proliferation
Improved angiogenesis and cellular migration
Increased collagen and elastin synthesis
Sustained hydration and tissue support

The addition of trehalose provides:

Anti-glycation protection
Antioxidant support
Stabilisation of hyaluronic acid for prolonged tissue activity

This dual-action system creates a more durable regenerative environment, supporting long-term dermal restructuring.

Anti-Glication and Regeneration Potential

Resteem™ delivers true biological regeneration, not temporary cosmetic enhancement.

Measurable increase in skin thickness on ultrasound
44% increase in cell proliferation vs competitor biostimulators
Up to 69% reduction in glycation markers (CML)
30% protective effect against glycation processes

Resteem™ consistently demonstrates:

Improved skin thickness and density
Enhanced elasticity and hydration
Reduction in wrinkles and fine lines
Improvement in acne scarring
Visible lifting and contour refinement

Three Benefits in One Range:

1. Anti-Ageing Prevention

Reduces glycation (AGEs formation)
Limits oxidative stress
Preserves collagen integrity

2. Regeneration & Rejuvenation

Improves skin quality and density
Enhances hydration and elasticity
Smooths fine lines and refines texture

3. Tissue Restructuring

Restores skin architecture.
Supports repair of damaged dermal structures
Improves scars (including post-acne)

Injection Science: Precision Matters

Resteem™ protocols are built around advanced injection techniques, including:

Intradermal microinjections
RTDI (Retrotracing Diagonal Injection)
Resteem™ Points Method (8 points per side)

Treatments are guided by:

Langer’s lines (collagen fibre orientation)
Blaschko vectors (cell migration pathways)

Langer’s lines and Blaschko’s vectors collectively influence cutaneous biodynamics, including the alignment of structural fibres and cellular architecture. They are integral in modulating mechanical stress distribution and interstitial fluid dynamics within the skin. Wrinkles tend to develop along these predefined pathways, making it clinically advantageous to align treatment techniques with these anatomical patterns to optimise therapeutic efficacy.

This ensures:

More effective regenerative response
Improved product distribution
Enhanced lymphatic flow

Positioning Resteem™ in Your Practice

Resteem™ allows practitioners to:

Move beyond volume-based aesthetics
Offer regenerative treatment protocols
Treat patients at earlier stages of ageing
Integrate seamlessly with device-based treatments

It is particularly valuable for:

Patients are not yet ready for fillers
Skin quality optimisation programmes
Combination treatment strategies

Resteem™ by Urgo Aesthetics is not simply another injectable. It is a bioregenerative platform designed to:

Reverse key ageing mechanisms
Restore dermal function
Deliver measurable, progressive results

It represents a next-generation approach to aesthetic medicine in which skin health becomes the primary endpoint.